An Expert Offers Important Facts and Advice on Living with Nasal Polyps

WORDS DR YOGESVARAN KANAPATY

FEATURED EXPERT
DR YOGESVARAN KANAPATY
Consultant Rhinologist and ENT – Head & Neck Surgeon
Columbia Asia Hospital–Bukit Jalil

Breathing should be effortless.

Yet, for many, nasal polyps disrupt this simple act. Imagine a persistent feeling of congestion, an unrelenting blockage that complicates every breath.

Nasal polyps, often unnoticed but profoundly impactful, can turn the breathing routine into a struggle.

WHAT ARE NASAL POLYPS?

Nasal polyps are usually non-cancerous outgrowths of the nasal mucosa. The nasal mucosa refers to inner lining the nasal cavity and sinuses.


More details about nasal polyps. Click on the image for a larger, clearer version.


NASAL POLYPS CAN AFFECT ONE’S SLEEP

Mechanical obstruction of the nasal passage by the polyps, together with nasal inflammation and congestion, leads to snoring and apnoea.

Someone experiencing these difficulties ends up with poor quality of sleep that can lead to an increased risk of various medical conditions such as heart problems.

HOW DO NASAL POLYPS COME ABOUT?

Nasal polyps are mainly due to the long-standing inflammation or irritation of the mucosa, which is lining cells and layers of the nasal cavity and sinuses.

Such inflammation or irritation is known as chronic rhinosinusitis or CRS.

CRS IS COMMONLY RELATED TO VARIOUS TYPES OF ALLERGIES

Long-standing allergies lead to the formation of multiple large polyps.

The longer the allergy, the more severe the presentation becomes. Consequently, treatment will become more challenging.

Hence, the earlier CRS is detected, the better. When detected early, CRS can be treated promptly with good control of the underlying allergies.

Careful, once the allergies recur, polyps can follow!

HOW CRS IS TREATED

The main goal of treatment of nasal polyps is to reduce the inflammation that causes the polyps.

Once the inflammation is controlled, the polyps will normally shrink in size, especially if it is small or in its early stage.

Steroid Sprays

These sprays remain the first-line treatment to achieve this.

Surgery

The second line for non-responsive cases or bigger polyps would be surgery. See the table for more details.

Surgical options come into play as the first option when the polyps are not allergic in nature, such as antrochoanal polyps or polyps of suspected neoplastic origin.

SURGERY IS OFTEN CONSIDERED IN THE FOLLOWING CIRCUMSTANCES:
  • Worsening symptoms.
  • Progressively enlarging polyps.
  • Recurrent sinus infections.
  • Decreased sense of smell and taste.
  • Breathing difficulties.
  • Sleep disturbances.
  • Worsening asthma attacks.
  • Complications that affect the orbit, which is the bony cavity that contains the eyeball (orbital complications) with, rarely, complications involving the cranium or the skull cavity (intracranial complications).
LET’S TALK ABOUT THE SURGERY
Short Downtime

It is a simple day-care procedure for medically fit patients with no contraindications; they can often return home on the same day.

Otherwise, a slightly longer stay of 2 to 3 days will suffice.

Potential Side Effects

The side effects are minor self-limiting bleed, mild discomfort, crusting, redness, and temporary distorted sensation of smell.

Mechanical injuries to the neighbouring structures, such as the eye and skull base, are uncommon.

Post-surgery Care

Post-surgery care is a highly important determinant of surgical success.

Regular nasal saline irrigation and regular sinus cavity debridement are recommended in early post-operative care interventions.

Post-operative antibiotics and systemic steroids are catered for on a patient-to-patient basis.

Moisture is critical for proper healing. Patients will need to moisturise and douche their nose at least 3 to 4 times a day, and for at least 4 to 6 weeks after surgery.

MONOCLONAL ANTIBODIES ARE A NEWER GROUP OF TREATMENTS FOUND EFFECTIVE FOR RECURRENT POLYPS UNAMENDABLE FOR STEROID AND SURGICAL INTERVENTION

Aspirin-exacerbated respiratory disease (AERD), also known as Samter’s Triad, is a chronic medical condition that consists of three clinical features: asthma, sinus disease with recurrent nasal polyps, and sensitivity to aspirin and other non-steroidal anti-inflammatory drugs.

Monoclonal antibodies show a promising outcome in these cases. However, this treatment involves a longer duration with a higher cost of treatment.

OTHER NON-INVASIVE TREATMENTS AVAILABLE IN MALAYSIA FOR NASAL POLYPS

Oral corticosteroids can be a non-specific consideration for nasal polyps. It is advised to be taken for a short term, bearing in mind the side effects, leading to the recurrence of polyps once suspended.

A newer tool of steroid-impregnated sinus implant is available overseas, but it is still in its early stage of proven effectiveness.

 

Invasive Mold Infections: A Rare but Deadly Fungal Disease

WORDS DR LOW LEE LEE

FEATURED EXPERT
DR LOW LEE LEE
Infectious Disease Physician
Sultanah Bahiyah Hospital
FUNGI: OUR FRIENDS & FOES (IT’S COMPLICATED)

Fungi are found naturally in our environment. There are many different types of fungi, over 2 million species however about 600 fungi have caused diseases.

Invasive fungal infections typically manifest as a severe and aggressive form of the disease, leading to corresponding to high prevalence and death rates if left untreated.

These infections include invasive mold infections.

INVASIVE MOLD INFECTIONS AT A GLANCE
  • Usually caused by Aspergillus (giving rise to invasive aspergillosis) but can also be caused by other rarer molds such as Mucormycetes (giving rise to mucormycosis).
  • These molds produce spores; most of us encounter these spores every day without getting ill, but people with compromised immune systems may develop complications as a result of these spores.
  • Despite invasive aspergillosis and mucormycosis being relatively uncommon, invasive mold infections are often life threatening. If left untreated, the mortality rates can reach 100%!
  • Various parts of the world reported superinfections of invasive aspergillosis and mucormycosis in patients with COVID-19, which are associated with increased risk of death. COVID-19 likely increases the risk for fungal infections because it weakens the immune system or due to certain therapies used for treatment such as steroids.
  • There are no specific symptoms, as symptoms can vary depending on the type of infection. This makes diagnosis an infection a challenging and sometimes complicated task!
Invasive Aspergillosis
Aspergillosis and how it affects our lungs. Click on the image for a larger, more detailed version.
  • Invasive aspergillosis is uncommon and occurs primarily in immunocompromised people.
  • Commonly seen in people that have undergone stem cell and other organ transplants (especially lung transplant), as well as in patients with blood-related cancers such as acute leukemia.
  • Typically affects the lungs, but it can also spread to other parts of the body.
Mucormycosis
  • Mucormycosis is rare and estimated to affect approximately 10,000 cases worldwide, barring India. If India is included the numbers rise to 910,000 cases annually!
  • Typically occurs in the sinuses of the nose or lungs; however it can spread to the brain and other organs as well.
COMMON SYMPTOMS OF A POSSIBLE INVASIVE MOLD INFECTION
  • Typical pneumonia symptoms including fever, chest pain, cough, coughing up blood, and shortness of breath
  • Sinus infection, which may be painful
  • Pain, tenderness, swelling and pressure around the eyes, cheeks, nose or forehead
  • One-sided facial swelling
  • Headaches
  • Nasal or sinus congestion
  • Black lesions on nasal bridge
HOW TO REDUCE YOUR RISK OF AN INVASIVE MOLD INFECTION
  • When performing activities that involve close contact with soil and dust, such as yard work or gardening, take care to wear shoes, long pants, and long-sleeved shirts
  • Whenever possible, avoid dusty areas like construction or excavation sites; wear a N95 mask when you have to visit these areas
  • Keep your house dry and mold-free
  • Avoid staying in a moldy home (even while it is being cleaned)